Speech Title: Self-assembly of carbohydrate-block copolymers : Glyconanparticles and nanostructured thin film Abstract: Current knowledge in modern molecular science allows for the preparation of a myriad of tailored nanomaterials, which play important and multifaceted roles in nanoscience and technology. Among the bottom-up strategies, self-assembly is an incredibly powerful concept in macromolecular engineering that offers an invaluable tool for the preparation of 2D and 3D discrete nanostructures, ranging from materials science to molecular biology, which are often not accessible by any other fabrication process. Using self-assembly as a synthetic tool, powerful chemistry and physico-chemistry protocols can be developed that are capable of organizing organic and inorganic building-blocks into unprecedented structures and patterns, over several length scales to create novel and innovative materials. In this context and during the last decades, block copolymers (BCP) systems have received considerable attention as a promising platform for preparing nanometer-scale structures and materials due to their self-assembling nature into periodic domains whether in solution (nanoparticles) or solid states. To date, numerous studies have been focused on the self-assembly of petroleum-based BCPs for potential applications in multidisciplinary fields, such as nanoparticles for drug delivery, or nano-organized films for biosensors, or nanolithography, etc. Such materials are derived from fossil resources that are being rapidly depleted and have negative environmental impacts. In contrast, carbohydrates are abundant, renewable and constitute a sustainable source of materials. This is currently attracting much interest in various sectors and their industrial applications at the nanoscale level will have to expand quickly in response to the transition to a bio-based economy. The self-assembly of carbohydrate BCP systems at the nanoscale level via the bottom-up approach, has allowed the conception of nanostructured thin films and nanoparticles (micelles, vesicles,…) whose external shell is made from carbohydrates. We will present recent results on the self-assemblies of carbohydrate-based block copolymer leading to nanoparticles presenting different shapes (spherical, cubic, …) and highly nanostructured thin films for nanobioelectronic applications. [1] Yingjie Liao, Kangping Liu,Wen-Chang Chen, Bin Wei & Redouane Borsali* Robust Sub-10 nm Pattern of Standing Sugar Cylinders via Rapid “Microwave Cooking” MACROMOLECULES 2019 Publication November 7, 2019 [2] Isono, Takuya, Kawakami, Nao Watanabe, Kodai, Yoshida, Kohei, Otsuka, Issei, Mamiya, Hiroaki, Ito, Hajime, Yamamoto, Takuya,Tajima, Kenji, Borsali, Redouane, Satoh, Toshifumi “Microphase separation of carbohydrate-based star-block copolymers with sub-10 nm periodicity” POLYMER CHEMISTRY DI 10.1039/c8py01745j, MAR 7 2019 [3] Y. Liao, W.-C. Chen, R. Borsali « Carbohydrate-Based Block Copolymer Thin Films: Ultrafast Nano-Organization with 7 nm Resolution Using Microwave Energy » Adv. Mater., 2017, First published: 6 July 2017, DOI: 10.1002/adma.201701645 [4] C.-C. Hung, Y.-C. Chiu, H.-C. Wu, C. Lu, C. Bouilhac, I. Otsuka, S. Halila, R. Borsali, S.-H. Tung, W.-C. Chen « Conception of Stretchable Resistive Memory Devices Based on Nanostructure-Controlled Carbohydrate-b-Polyisoprene Block Copolymers » Adv. Funct. Mater, First published: 6 February 2017 DOI: 10.1002/adfm.201606161 [5] C. Chiu, I. Otsuka, S. Halila, R. Borsali &.W.-C. Chen, « High-Performance Nonvolatile Transistor Memories Of Pentacence Using The Green Electrets of Sugar-Based Block Copolymers And Their Supramolecules, » Adv. Funct. Mater., 24(27), 2014, 4240-4249 [6] J.D. Cushen, I. Otsuka, C.M. Bates, S. Halila, S. Fort, J.A. Easley, E. Rausch, A. Thio, R. Borsali, C.G. Willson & C.J. Ellison, Oligosaccharide/Silicon-Containing Block Copolymers - 5 Nm Features for Lithographic Applications », ACS NANO, 6(4), 2012, 3424-3433 [7] C. Giacomelli, V. Schmidt, K. Aissou & R. Borsali « Block Copolymer Systems: From Single Chain to Self-Assembled Nanostructures » Langmuir (Invited Feature Article), 26 (20), 2010, 15734-15744. Biography: R. Borsali ACTUAL POSITIONS: • Director of PolyNat Carnot Institute (from 2011 –until today) gathering 6 Laboratories and 2 Technical Centers – Grenoble (about 400 Persons) “High-added Value for, innovative, functional, biosourced and flexible Materials” http://www.polynat.eu/en • Group Leader (from 2010-until today) – (15-20 persons) “Self-Assembly of Block copolymer systems: Nanoparticles and Thin Films” (CNRS) https://cermav.cnrs.fr/en/the-teams/physico-chemistry-and-self-assembly-of-glycopolymers/ • Co-Director of Green Material Institute, NTU, Taipei, Taiwan since 2021 EARNED DEGREES: • Priv. Doz./ Habilitation to lead Research, Joseph Fourier University, Grenoble, France (1992) • PhD in Polymer Sciences, Louis Pasteur University, Strasbourg, France (1988) • MASTER in Polymer Sciences, Louis Pasteur University, Strasbourg, France (1985) PUBLICATIONS, CONFERENCES & SUPERVISOR: • 287 Publications; H-index= 45, Citations: 6700, Average Citation : 26, • >120 invited international conferences • Chair/co-Chair of 24 International Conferences on « Polymers & Colloids » • Supervisor of 27 Post-docs, Supervisor or Co-supervisor of 43 Phd students, Supervisor of 24 Masters